28 year old male with seizures

 January 11,2022 


This is online E-blog, to discuss our patient de-identified health data shared after taking her guardian's signed informed consent.


Here we discuss our individual patient problems through series of inputs from available global online community of experts with an aim to solve the patients clinical problem with current best evidence based input.


This E-blog also reflects my patient's centred online learning portfolio.


I have been given this case to solve in an attempt to understand the topic of "Patient Clinical Data Analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan. 


CASE SCENARIO

28 Year old male who is sales man by occupation presented to casualty with complaints of

Seizures -15 days back 

Fever with chills and rigors -since 10 days

Cough -  since 10 days.


HISTORY OF PRESENT ILLNESS:


 Patient was apparently asymptomatic 11 months back , then he noticed rapid  loss of weight which was about 10 kgs in a month

In the month of April,he went to a local hospital and after routine investigations found out his creatinine levels are high and diagnosed him with hypertension

He then went to a hospital in Hyderabad for confirmation and there he was told to start dialysis

Then on April 16 th ,he came to our hospital and was tested positive for COVID 19 and started on treatment. 

From the month of April ,he was not going to work and stayed at home doing simple daily works .

Then he came to our hospital again in the month of June and had 28 dialysis sessions from June 24 th to September 19 th , regularly.

After that , he decided to remove central line and shift to AV fistula , which was failed once , then he tried again so was not on dialysis for 3 months( september to december)


•Then he had SEIZURES 15 days back , which was 3 episodes

 each episode of seizure lasted for 3 to 5 minutes, associated with uprolling  of eyeballs and frothing from mouth , there was post ictal confusion for about 30 minutes after 1st episode and about 10 to 15 minutes after 2nd and 3rd episode

Episode was not  associated with biting of tongue and involuntary micturition 

After 1st episode he was taken to nearby hospital for which  he was admitted and treated for 3 days and then discharged.

After going to home ,he had 2 nd seizure episode at around 12 am ,which was for 3 -5 minutes , and then he had another 3 rd  episodes at 3 am in the morning.

 Then he came back to our hospital , again. he was started  dialysis 

-he also has  complaints of shortness of breath ( Grade 2) which is insidious in onset and gradually progressive and aggravated  more during lifting weights.

He also has  cough since 10 days,not associated with sputum .

He also has fever since 10 days 

There was decreased urine output, and decreased appetite  

chest pain since 10 days ,which was more during lying down flat 


No history of burning micturition,red colour urine , nausea, vomiting, loose stools, head aches, confusion, dizziness

Patient was normal and shifted to ward ,but later he developed fever yesterday ,which is of high grade ,then he again was shifted to ICU . 




PAST HISTORY

 •Known case of hypertension since 11 months

•Not a known case of diabetes, asthma, TB , any CHD


FAMILY HISTORY

 no significant family history


PERSONAL HISTORY

 ▪Diet-mixed

▪ Appetite-decreased

▪Bowel movements-Regular

▪Bladder movements-Decreased since 10 days

▪Sleep- adequate

▪Habits- he used to drink beer  and stopped since 8 months, and not a smoker 

GENERAL EXAMINATION


 ▪Patient is conscious , coherent and cooperative and well oriented to time place 

and person, moderately built and moderately nourished


- Pallor- present 



-Icterus-absent

-Cyanosis-absent

-Clubbing-absent

-Lymphadenopathy-absent

-Edema-absent


        



VITALS


Temperature-100.3F 

Pulse rate-86 beats per minute

Respiratory rate-14 cycles per minute

BP-160/100 mm of hg 

Spo2-98%

GRBS-130 mg%

 

SYSTEMIC EXAMINATION

 

▪CVS-- s1 ,s2 heard no murmurs

 • Respiratory system- normal vesicular breath sounds heard

    Pleural rub was heard on right side of lung 

 • Abdomen- no tenderness is felt no. . palpable mass seen, no abdominal distension.


CNS-

-Patient is conscious

Speech -normal

No signs of meningeal irritation

SENSORY EXAMINATION,- touch, pain , vibration present

Motor examination 

  Bulk of muscle - No wasting was found 

 Tone of muscles is normal

•Power of muscles 

                           Right               left 

            Biceps.    5/5.                   5/5

            Triceps.   5/5.                    5/5

Extensors of knee -5/5               5/5

      Flexors of knee  5/5            5/5

   Exetnsors of hip  5/5.               5/5

      Flexors of hip.   5/5                5/5

                     

REFLEXS:-

 

• Deep tendon reflexes


                        Right.   . Left

 Knee jerk.     +2            +2

  Ankle reflex +2          +2    

  Biceps               +2          +2      

  Triceps.             +2           +2

  Supinator.       +2              +2    

  

•Gait -normal


Coordination tests 

Finger nose test-able to perform- 

knee heel test- able to operform

 Romberg sign- negative 

No involuntary movements are noted

INVESTIGATIONS


  Liver function tests 


Haemogram 

CBP:
HB : 5.6gm/dl
TLC: 4000cells/mm³
PLT: 1.99 lakh/mm³

ABG
PH: 7.12
PCO2: 13.1
HCO3:6.9
   
RFT
UREA : 239mg/dl
CREATININE : 16.8
URIC ACID : 16.8
CALCIUM : 8.2
Na+: 145
K+: 5.7
Cl- 107
 
LFT
ALT : 08
ALP : 164. 


2D echo





Renal function tests 



ECG  









 

PROVISIONAL DIAGNOSIS: 


UREMIC ENCEPHALOPATHY WITH CkD ON MHD WITH HYPERTENSIVE NEPHROPATHY.



TREATMENT

1) Fluid restriction( 1 ltr per day)


2)salt restriction( 2.4 g per day)


3)Tab NODOSIS( 550mg )PO/OD


4)Tab SHELCAL(500 mg) PO/OD


5)Tab OROFER Po/ OD..


6)Tab LASIX 40 mg PO / BD


7)TAB NICARDIA 10 mg PO/BD











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